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Inventi Impact: Ophthalmology

Articles

  • Inventi:hvs/30/12
    ONE-YEAR RESULTS OF PHOTODYNAMIC THERAPY COMBINED WITH INTRAVITREAL RANIBIZUMAB FOR EXUDATIVE AGE-RELATED MACULAR DEGENERATION
    30-Jun-2012 Research 2012 : July - September
    Tomoko Nakamura, Akio Miyakoshi, Kazuya Fujita, Tatsuya Yunoki, Keiichi Mitarai,\r\nShuichiro Yanagisawa, Chiharu Fuchizawa, Atsushi Hayashi

    Purpose. To evaluate the effects of photodynamic therapy (PDT) combined with intravitreal injection of ranibizumab (IVR) for\r\nexudative age-related macular degeneration (AMD). Methods. Retrospective case series. Thirty eight eyes of 38 patients with\r\nexudative AMD underwent combined therapy consisting first of IVR, followed by PDT within a week and the second IVR at 1\r\nmonth. All patients were followed up for more than 12 months. The best corrected visual acuity (BCVA) and central macular\r\nthickness (CMT) were examined. Results. The mean number of IVR and PDT sessions were 2.9 �± 1.3 and 1.1 �± 0.3, respectively.\r\nThe mean BCVA and CMT were significantly improved to 0.38 logMAR units (P < 0.01) and 240 �µm (P < 0.01) at 12 months,\r\nrespectively. Thirty-six of 38 eyes (94.8%) improved or maintained BCVA at 12 months. Conclusion. PDT combined with IVR for\r\nexudative AMD was effective at improving visual acuity and CMT with a low recurrence rate for 12 months.

    How to Cite this Article
    CC Compliant Citation: Tomoko Nakamura, Akio Miyakoshi, Kazuya Fujita, et al., â??One-Year Results of Photodynamic Therapy\r\nCombined with Intravitreal Ranibizumab for Exudative Age-Related Macular Degeneration,â? Journal of Ophthalmology, vol. 2012,\r\nArticle ID 154659, 8 pages, 2012. doi:10.1155/2012/154659.
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